Rheumatoid Arthritis: The JAK/STAT Pathway and Clinical Autoimmunity

The goal of this activity is to provide learners with a better understanding of immune mechanisms related to the pathogenesis of autoimmunity and rheumatoid arthritis. This module incorporates clinical scenarios and immunologic basic principles. In the module, learners acquire basic science knowledge, and then apply their understanding of JAK-kinase inhibition to the clinical management of patients. There is no fee for the online module. 

We will provide collective feedback on module questions as value added to your participation.

The innovative adaptive learning platform used for this module will present content customized to each learner depending on baseline level of expertise. Depending on your baseline level of expertise, the module can be completed in as little as 30 minutes. The module may be completed in a single session or in small portions over time and may be accessed from any device. 

Instructions to Complete the Module:

  1. Click on the blue "Register/Take Course" tab above 
  2. You will be prompted to log in or register
  3. After you log in or register, we will receive notification of your enrollment
  4. We will email you a deidentified username, password and link to the adaptive learning module within 1 business day
  5. Use the login information provided by email to select and complete the module
  6. Provide any feedback 

Target Audience

This activity is intended for physicians and advanced practice providers in the field of rheumatology. Dermatologists and gastroenterologists are a secondary target audience. 

Additional Background Information:

This is an educational research project conducted by the Mass General Brigham Office of Professional Development Knowledge Translation Lab. Dr. Robert Birnbaum is the Principal Investigator, and Dr. Simon Helfgott is the Subject Matter Expert. All information derived from this study and data produced from your participation will be confidential. Data will be de-identified to protect healthcare provider information accessed by any constituencies. Data is collected for evaluating the efficacy of the learning methodology and to discern training needs — not to supervise or determine the level of your individual clinical acumen or skills. This educational research project is supported by funding from Eli Lilly. The content was solely developed by subject matter experts at Mass General Brigham.


Please contact us at partnerscpd@partners.org.

Target Audience

This activity is intended for rheumatologists, gastroenterologists, and dermatologists.

Additional Information

Provided by: 

Mass General Brigham

Course summary
Course opens: 
Course expires: 

Course Director:

Robert J. Birnbaum, MD, PhD

Vice President, Continuing Professional Development, Mass General Brigham

Assistant Professor, Psychiatry, Harvard Medical School


Subject Matter Expert:

Simon Helfgott, MD

Director of Education & Fellowship Training, Brigham and Women's Hospital

Associate Professor of Medicine, Division of Rheumatology, Inflammation and Immunity, Harvard Medical School

This activity does not include CME credit.


Please login or register to take this course.