Description

The presentation will focus on the epidemiology and risk factors of bone loss among individuals living with HIV. It will also focus on the effects of antiretroviral medications on bone health and potential interventions to treat and prevent osteoporosis among people living with HIV.

Live broadcasts begin promply at 8 am EST.

Each live broadcast will be available as an on-demand archived version. 

Learning Objectives

Upon completion of this activity, participants will be able to:

1. Assess risk factors in HIV+ patients which contribute to osteoporosis risk.
2. Identify HIV medications associated with increased osteoporosis risk and develop alternative treatment plans.
3. Describe evidence-based interventions to treat osteoporosis.

Target Audience

This activity is intended for HIV clinicians and caregivers, including physicians, nurse practitioners, and physicians' assistants. 

Faculty

Janet Lo, MD, M.MSc
Assistant Professor of Medicine
Harvard Medical School
Clinical Investigator, Program of Nutritional Metabolism
Endocrinologist, Neuroendocrine and Pituitary Tumor Clinical Center
Massachusetts General Hospital

Janet Lo, M.D., M.MSc. is Assistant Professor of Medicine at Harvard Medical School, Endocrinologist in the MGH Neuroendocrine and Pituitary Tumor Clinical Center and a Clinical Investigator in the Program of Nutritional Metabolism at the Massachusetts General Hospital. She received her medical degree from Columbia University College of Physicians and Surgeons, New York, and completed her internship and residency in internal medicine at Columbia University Medical Center New York-Presbyterian Hospital and fellowship in endocrinology at Massachusetts General Hospital. She also received a master’s degree in Clinical Investigation from Harvard Medical School’s Scholars in Clinical Science Program.

Dr. Lo’s clinical research focuses on the endocrine and cardiovascular complications of HIV disease. She has studied the hormonal factors associated with altered glucose homeostasis and visceral adiposity in people living with HIV. In addition, her research work has also demonstrated that people living with HIV have increased coronary atherosclerosis, that markers of innate immune activation are associated with increased coronary atherosclerosis in individuals living with HIV and that statin therapy reduces coronary atherosclerosis in the HIV patient population. She is currently the PI of NHLBI RO1 -funded clinical studies to investigate gastrointestinal epithelial integrity and its role in immune activation and cardiovascular disease, and NIDDK Harvard Nutrition Obesity Research Center-funded studies on bone health and metabolic disease in people with HIV. She is also the protocol chair of ACTG A5363, currently under protocol development, targeting CCR2 and CCR5 to reduce innate immune activation and arterial inflammation in people living with HIV.

She teaches medical students, residents and fellows at the Massachusetts General Hospital through the Endocrine Consult service and in clinic at the MGH Neuroendocrine and Pituitary Tumor Clinical Center. She also teaches Harvard Medical School students in the Longitudinal Course in Clinical Medicine. She is the recipient of the 2017 MGH Division of Endocrinology Gilbert H. Daniels Award for Excellence in Teaching.

CME/CE Information

Accreditation

Partners HealthCare System is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Partners HealthCare System designates this live activity for a maximum 1 AMA PRA Category 1 Credit^TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

FACULTY DISCLOSURE STATEMENTS 
In accord with the disclosure policy of Partners HealthCare System as well as guidelines of the Accreditation Council for Continuing Medical Education (ACCME), planners, speakers and anyone who may have an influence on the content of the activity have been asked to disclose any relationship they or their spouse/partner have to companies producing pharmaceuticals, medical equipment, devices, etc. that may be germane to the content of their presentation. Such disclosure is not intended to suggest or condone bias, but provides participants with information that might be of potential importance to their evaluation of a given presentation.

RESOLUTION OF CONFLICTS OF INTEREST (COI)
Partners HealthCare System has implemented a process to resolve potential COIs for this CME activity to help ensure content objectivity, independence, fair balance and ensure that the content is aligned with the interest of the public.

The following planner and/or their spouse/partner have reported no relevant financial relationship with a commercial interest:
Jacqueline Chu, MD
Virginia Triant, MD, MPH

The following planner and/or their spouse/partner have reported a relevant financial relationship with a commercial interest:
Rajesh T. Gandhi, MD
Grant Funding: Gilead, Merck, ViiV
Consultant: Theratechnologies; EMD Serono

The following speaker and/or their spouse/partner have reported a relevant financial relationship with a commercial interest:
Janet Lo, MD, M.MSc
Honorarium: Gilead Sciences
Consultant: Viiv Healthcare

Hardware/Software Specifications: 

This internet-based CME activity is best experienced Microsoft Internet Explorer 9.0 or later, Mozilla Firefox 13 or later, Chrome 16 or later, Safari (version 5 or later)

This Web site requires that JavaScript and session cookies be enabled. Certain activities may require additional software to view multimedia, presentation, or printable versions of the content. These activities will be marked as such and will provide links to the required software. That software may be: Adobe Flash, Adobe Acrobat, and Microsoft PowerPoint.

Optimal System Configuration: 
Flash Player: Adobe Flash Player 10.1+
Browser: Firefox 13+, Internet Explorer 9.0+, Safari 13+, or Google Chrome 16+
Operating System: Windows Vista,7,8 or Mac OS X 10.4+
Internet Connection: 1 Mbps or higher

Minimum Requirements: 
Windows PC: 
Intel Pentium 4 or equivalent with 2.33 GHz processor; Windows XP; 512 MB RAM; Video Card at least 64MB of video memory; Sound Card at least 16-bit; Macromedia Flash Player 10 or higher, audio playback with speakers for programs with video content; Firefox 3+, Internet Explorer 7.0+, Safari 4+, Google Chrome, or Opera
Macintosh: 
Mac OS X 10.3 or higher with latest updates installed; 1.83MHz Intel Core Duo or faster; RAM: 128MB or more; Video Card: at least 128MB of video memory; Sound Card: at least 16-bit