
Cardiovascular-Kidney-Metabolic Care: Core Principles and Innovations
The expanding prevalence and intersectionality of cardiovascular, kidney, and metabolic (CKM) diseases has brought the need for high-quality interdisciplinary care into sharp focus. However, comprehensive and individualized care for persons with or at risk for CKM diseases remains limited by gaps in education, implementation, and teamwork. As such, we developed the “Cardiovascular-Kidney-Metabolic Care: Core Principles and Innovations” educational course program at Mass General Brigham. This course aims to provide an action-oriented, comprehensive, and interdisciplinary review of core CKM concepts for healthcare professionals. This fast-paced, interactive and case-based educational experience is designed and led by multidisciplinary faculty at Mass General Brigham, a leading healthcare institution, and features presentations from experts from around the world.
Target Audience
This activity is intended for physicians and associate physicians in primary care and internal medicine specialties as well as clinical pharmacists.
Learning Objectives
Upon completion of this activity, participants will be able to:
- Discuss the overlapping pathophysiological mechanisms and shifting epidemiology of CKM diseases.
- Apply up-to-date CKM screening guidelines in routine clinical care.
- Apply timely diagnosis and risk stratification of CKM risk factors and diseases.
- Identify optimal approaches for the prevention and treatment of CKM diseases.
Additional Information

Day 1 | December 2, 2026 | 8:00am-5:00pm
Foundations: Understanding CKM Diseases as One Entity
| 8:00am | Introduction & Objectives | John Ostrominski, Ashima Chadha, Zeb Saeed |
CKM Health – From Shared Disease Mechanisms to Intersectional Guidelines | |
| 8:15 | The CKM Syndrome: From Concept to Clinical Action | Chiadi E. Ndumele |
| 9:00 | Centrality of Kidney Health in CKM Syndrome | Janani Rangaswami |
| 9:45 | Q&A/Panel Discussion | Chiadi E. Ndumele & Janani Rangaswami |
| 10:05 | Break |
But First, Detection: The CKM Screening Bundle | |
| 10:20 | Don’t Weight and See: Comprehensive Adiposity Screening in CKM | Lindsay Fourman |
| 10:50 | Interactive Case: Anthropometrics in Action | Lindsay Fourman |
| 11:05 | Beyond A1c: Screening for Prediabetes and Diabetes | Marie McDonnell |
| 11:35 | Interactive Case: Diabetes Screening | Marie McDonnell; Viral Shah; Nuha ElSayed |
| 11:50 | Q&A/Panel Discussion | Lindsay Fourman & Marie McDonnell |
| 12:00pm | Lunch Break |
| 1:00 | Screening for MASLD/MASH | Kathleen E. Corey |
| 1:45 | Interactive Case: MASLD/MASH Screening | Kathleen E. Corey |
| 2:00 | The Modern Age of Renal Risk Assessment: CKD Detection and Its Cardiovascular Implications | Finnian Mc Causland |
| 2:45 | Interactive Case: Microalbuminuria is No Small Matter | Finnian Mc Causland |
| 3:00 | Q&A/Panel Discussion | Kathleen E. Corey; Finnian Mc Causland |
| 3:15 | Break |
| 3:30 | Screening for Cardiovascular Disease | Pradeep Natarajan |
| 4:15 | Interactive Case | Pradeep Natarajan |
| 4:30 | Q&A/Panel Discussion | John Ostrominski; Ashima Chadha; Zeb Saeed |
| 5:00pm | Adjourn |
Day 2 | December 3, 2026 - | 8:00am-5:15pm
Prevention and Treatment of CKM Conditions (Core Concepts)
| 8:00am | Introduction & Objectives | John Ostrominski, Ashima Chadha, Zeb Saeed |
Moving Upstream: Foundations for Primordial and Primary Prevention of CKM Diseases | |
| 8:15 | Movement as Medicine: Physical Activity Guidelines and Implementation | Meghan Wasfy |
| 8:45 | From Plate to Prevention: The Latest Updates in Evidence-Based Nutrition | Patricia G. Davidson, DCN, RDN, CDCES, LDN, FAND, CHSE, FADCE |
| 9:15 | The Silent Amplifier: Sleep and Cardiometabolic Risk | Susan Redline |
| 9:45 | Q&A Panel/Panel Discussion | Patricia G Davidson, DCN, RDN, CDCES, LDN, FAND, CHSE, FADCE; Susan Redline |
| 10:00 | Break |
After Diagnosis: Goals for Risk Factor Treatment | |
| 10:15 | Risk Factor Control Case Discussions: Multidisciplinary Perspectives on Risk Factor Management | Lee-Shing Chang; David Steele |
| 11:00 | Q&A/Panel Discussion | Lee-Shing Chang; David Steele |
| 11:20 | Lunch Break |
Treating and Preventing CKM Diseases Simultaneously: Intersectional CKM Therapies | |
| 12:20pm | SGLT2 Inhibition as a Cardiorenal Therapy: Beyond Glucose Lowering | Alice YY Cheng |
| 1:10 | Nutrient Stimulated Hormone-Based Therapy: Beyond Weight Loss to Organ Protection | Vanita Aroda |
| 1:50 | Targeting the Mineralocorticoid Receptor Pathway | Muthiah Vaduganathan |
| 2:30 | Q&A/ Panel Discussion | Alice YY Cheng; Vanita Aroda; Muthiah Vaduganathan |
| 2:45 | Break |
| 3:00 | Metabolic Surgery: Resetting the Gut-Metabolic Axis in CKM | Abdelrahman Nimeri |
| 3:45 | Bridging the Gap: Endoscopic Bariatric and Metabolic Therapies | Pichamol (Sigh) Jirapinyo |
What’s Next? Potential CKM Therapies of Tomorrow | |
| 4:15 | Evolving Metabolic Therapeutic Pipeline | Deborah Wexler |
| 4:30 | Evolving Kidney Therapeutic Pipeline | Sahir Kalim |
| 4:45 | Evolving Cardiovascular Therapeutic Pipeline | Paul Ridker |
| 5:00 | Q&A/Panel Discussion | Deborah Wexler; Sahir Kalim; Paul Ridker |
| 5:15pm | Adjourn |
Day 3 | December 4, 2026 | 8:00am-3:30pm
CKM In the Real World: Putting it Together
| 8:00am | Introduction & Objectives | John Ostrominski; Ashima Chadha; Zeb Saeed |
Order of Operations: When and How to Intervene | |
| 8:15 | Do We Need to Intervene in CKM Stage 0? From Primary to Primordial Prevention | John Ostrominski |
| 9:00 | Break |
| 9:15 | Treating CKM Syndrome Stage 2-3: How to Start? | Kathy Tuttle |
| 9:45 | CKM Cases: Mitigating Adverse Events to Maintain Lifesaving Therapies | Zeb Saeed; Ashima Chadha |
| 10:30 | CKM in Older Adults | Julia Lowenthal |
| 11:15 | Q&A/Panel Discussion | Katherine Tuttle; Zeb Saeed; Ashima Chadha; Julia Lowenthal |
| 11:30 | Lunch Break |
| 12:30pm | CKM in ESRD: Screening for and Managing Cardiovascular Risk in the Dialysis Population | Mengyao Tang |
| 1:15 | CKM in Pregnancy/Postpartum | Michael Honigberg |
| 2:00 | Q&A Panel | Mengyao Tang; Michael Honigberg |
| 2:15 | Break |
| 2:30 | Focus Groups: What Can We Learn from Each Other in CKM Care? | Zeb Saeed; Ashima Chadha; John Ostrominski |
| 3:00 | Debrief | Zeb Saeed; Ashima Chadha; John Ostrominski |
| 3:15 | Concluding Remarks Panel | Zeb Saeed; Ashima Chadha; John Ostrominski |
| 3:30pm | Adjourn |
Course Directors
Zeb Saeed, MD
Instructor in Medicine, Harvard Medical School;
Division of Endocrinology, Diabetes and Metabolism,
Department of Medicine, Brigham and Women’s Hospital
Ashima Chadha, MD
Division of Nephrology, Department of Medicine,
Brigham and Women’s Hospital,
Massachusetts General Hospital
John W. Ostrominski, MD MPH
Division of Cardiovascular Medicine, Department of Medicine,
Brigham and Women’s Hospital
Faculty
Vanita R. Aroda, MD
Associate Professor of Medicine, Harvard Medical School;
Director, Diabetes Clinical Research,
Division of Endocrinology, Diabetes & Hypertension,
Department of Medicine,
Brigham and Women’s Hospital
Rhanderson Cardoso, MD, MHS
Assistant Professor of Medicine, Harvard Medical School;
Division of Cardiovascular Medicine, Department of Medicine,
Brigham and Women’s Hospital,
Brigham and Women’s Faulkner Hospital
Lee-Shing Chang, MD
Instructor in Medicine, Harvard Medical School;
Division of Endocrinology, Diabetes & Hypertension,
Department of Medicine,
Brigham and Women’s Hospital
Kathleen E. Corey, MD, MPH, MMSc, FAASLD
Associate Professor of Medicine, Harvard Medical School;
Director, MGH Steatotic Liver Disease Program,
Division of Gastroenterology, Department of Medicine,
Massachusetts General Hospital
Lindsay T. Fourman, MD
Assistant Professor of Medicine, Harvard Medical School;
Associate Director, Lipid and Metabolism Associates,
Metabolism Unit, Department of Medicine,
Massachusetts General Hospital
Michael C. Honigberg, MD, MPP, FACC, FAHA
Assistant Professor of Medicine, Harvard Medical School;
Cardiovascular Disease Prevention Center,
Cardiology Division, Department of Medicine,
Corrigan Women's Heart Health Program,
Associate Member, Center for Genomic Medicine
Massachusetts General Hospital
Associate Member, Broad Institute of MIT and Harvard
Pichamol (Sigh) Jirapinyo, MD, MPH, DABOM, FASGE, FACG, AGAF
Assistant Professor of Medicine, Harvard Medical School;
Director of Bariatric Endoscopy Fellowship,
Division of Gastroenterology, Hepatology and Endoscopy,
Department of Medicine, Brigham and Women’s Hospital,
Director of Bariatric Endoscopy, VA Boston Health Care
Sahir Kalim, MD, MMSc, FASN
Associate Professor of Medicine, Harvard Medical School;
Physician, Division of Nephrology, Department of Medicine,
Massachusetts General Hospital,
Co-Director, MGH Kidney Research Center
Julia V. Loewenthal, MD
Assistant Professor of Medicine, Harvard Medical School;
Division of Aging, Department of Medicine,
Brigham and Women’s Hospital
Nicholas A. Marston, MD, MPH
Assistant Professor of Medicine, Harvard Medical School;
Division of Cardiovascular Medicine, Department of Medicine,
Brigham and Women’s Hospital
Finnian R. McCausland, MBBCh
Associate Professor of Medicine, Harvard Medical School;
Division of Nephrology, Department of Medicine,
Brigham and Women’s Hospital
Marie E. McDonnell, MD
Associate Professor of Medicine, Harvard Medical School;
Chief, Diabetes Section, Division of Endocrinology, Diabetes, and Hypertension,
Department of Medicine, Brigham and Women’s Hospital
Abdelrahman A. Nimeri, MD, FACS, FASMBS
Associate Professor of Surgery, Harvard Medical School;
Director, Metabolic & Bariatric Surgery,
Department of Surgery, Mass General Brigham
Susan Redline, MD, MPH
Peter C. Farrell Professor of Sleep Medicine, Harvard Medical School;
Professor, Department of Epidemiology, Harvard T.H. Chan School of Public Health;
Division of Sleep and Circadian Disorders, Department of Medicine,
Brigham and Women’s Hospital
Paul M. Ridker, MD, MPH
Eugene Braunwald Professor of Medicine, Harvard Medical School;
Professor, Department of Epidemiology, Harvard T.H. Chan School of Public Health;
Director, Center for Cardiovascular Disease Prevention,
Division of Preventative Medicine, Department of Medicine,
Brigham and Women’s Hospital
David J.R. Steele, MD
Assistant Professor of Medicine, Harvard Medical School;
Division of Nephrology, Department of Medicine,
Massachusetts General Hospital
Mengyao Tang, MD
Instructor in Medicine, Harvard Medical School
Division of Nephrology, Department of Medicine,
Massachusetts General Hospital
Muthiah Vaduganathan, MD MPH
Assistant Professor of Medicine, Harvard Medical School;
Co-Director, Center for Cardiometabolic Implementation Science,
Division of Cardiovasular Medicine, Department of Medicine,
Brigham and Women’s Hospital
Meagan M. Wasfy, MD, MPH
Associate Professor of Medicine, Harvard Medical School;
Division of Cardiovascular Medicine, Department of Medicine,
Massachusetts General Hospital
Deborah J. Wexler, MD
Associate Professor of Medicine, Harvard Medical School;
Division of Endocrinology, Department of Medicine,
Massachusetts General Hospital
GUEST FACULTY
Alice Y.Y. Cheng, MD, FRCPC
Endocrinologist, Trillium Health Partners & Unity Health Toronto;
Associate Professor, University of Toronto, Canada
Patricia G. Davidson, DCN, RDN, LDN, CDCES, CHSE, FAND, FADCES
Professor of Nutrition,
West Chester University,
West Chester, PA
Chiadi E. Ndumele, MD, PhD, MHS
Associate Professor of Medicine and Epidemiology,
Director of Obesity and Cardiometabolic Research,
Director of the Heart Failure Prevention Program,
Division of Cardiology, Johns Hopkins University,
Baltimore, MD
Brendon Neuen, MBBS(Hons) MSc(Oxon) PhD FRACP FASN
Program Lead, Renal and Metabolic,
Nephrologist and Director, Kidney Trials Unit, Royal North Shore Hospital;
Clinical Associate Professor, University of Sydney,
Conjoint Associate Professor, Faculty of Medicine, UNSW Sydney
Australia
Janani Rangaswami, MD, FACP, FCRS, FAHA
Professor of Medicine, Attending Nephrologist and Director, Cardiorenal Program,
Washington University School of Medicine and Health Sciences,
Washington, D.C.
In support of improving patient care, Mass General Brigham is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
Credit Designation Statements
AMA PRA Category 1 CreditsTM
Mass General Brigham designates this live activity for a maximum of 22.75 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Physician Assistants
Mass General Brigham has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 22.75 AAPA Category 1 CME credits. PAs should only claim credit commensurate with the extent of their participation.
Pharmacists
This activity provides 22.75 contact hours (22.75 CEUs) of continuing education credit. ACPE Universal Activity Number (UAN): JA0007437-0000-26-007-L01-P
Available Credit
- 22.75 AAPA Category I CME
- 22.75 ACPE Pharmacy
- 22.75 AMA PRA Category 1 Credit™
- 22.75 Participation
Price
Tuition type | Early Bird (on or before October 23, 2026) | Regular Tuition (after October 23, 2026) |
Physician | $795.00 | $895.00 |
Nurses (NPs; APRNs; RNs) | $695.00 | $795.00 |
Physician Assistants | $695.00 | $795.00 |
Mental Health Professionals (Psychologists; Social Workers; Counselors) | $695.00 | $795.00 |
| Clinical Pharmacists | $695.00 | $795.00 |
Other Health Care Professionals | $695.00 | $795.00 |
Residents and Fellows | $595.00 | $695.00 |
Cancellation Policy:
Registrations cancelled on or before November 20, 2026 will be refunded, less a $105 administrative fee. Registrations cancelled after November 20, 2026 will not be refunded.
Contact [email protected] if you require assistance in cancelling your online registration.

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