Description

This presentation will focus on the virology, clinical features, natural history, and management of HBV. It will cover hepatotoxicity of ARV agents, as well as the severity of and assessment of liver disease in patients with HIV. It will also define fatty liver disease and discuss its diagnosis.

Live broadcasts begin promply at 8 am EST.

Each live broadcast will be available as an on-demand archived version.

Learning Objectives

Upon completion of this activity, participants will be able to:

1. Identify which antiretroviral agents may cause liver toxicity.
2. Implements diagnostic screening algorithms to identify patients with fibrosis and cirrhosis, and assess risk factors contributing to development and progression of liver disease in patients living with HIV.
3. Describe the accelerated progression of liver disease in HIV coinfection with hepatitis B or hepatitis C
4. Define and diagnose fatty liver disease.

Target Audience

This activity is intended for HIV clinicians and caregivers, including physicians, nurse practitioners, and physicians' assistants.

Faculty

Raymond Chung, MD
Associate Professor of Medicine
Harvard Medical School
Vice Chief, Gastrointestinal Division
Massachusetts General Hospital
Director of Hepatology and Liver Center
Massachusetts General Hospital
Medical Director, Liver Transplant Program
Massachusetts General Hospital

Raymond Chung, MD is the Director of Hepatology and Liver Center at Massachusetts General Hospital and an Associate Professor of Medicine at Harvard Medical School. Dr. Chung completed his B.A. at Harvard College and his MD from Yale University School of Medicine. He completed a residency in Internal Medicine and a fellowship in Gastroenterology and Hepatology at the Massachusetts General Hospital. Dr. Chung’s focus has been fundamental and translational research in HCV infection. Major focus of his research has been elucidating the basis for the observed accelerated liver disease pathogenesis in HCV-HIV coinfection. In this regard, his research has made important contributions to the current understanding of hepatic pathogenesis of coinfection.

CME/CE Information

Accreditation

Partners HealthCare System is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Partners HealthCare System designates this live activity for a maximum 1 AMA PRA Category 1 Credit^TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

FACULTY DISCLOSURE STATEMENTS 
In accord with the disclosure policy of Partners HealthCare System as well as guidelines of the Accreditation Council for Continuing Medical Education (ACCME), planners, speakers and anyone who may have an influence on the content of the activity have been asked to disclose any relationship they or their spouse/partner have to companies producing pharmaceuticals, medical equipment, devices, etc. that may be germane to the content of their presentation. Such disclosure is not intended to suggest or condone bias, but provides participants with information that might be of potential importance to their evaluation of a given presentation.

RESOLUTION OF CONFLICTS OF INTEREST (COI)
Partners HealthCare System has implemented a process to resolve potential COIs for this CME activity to help ensure content objectivity, independence, fair balance and ensure that the content is aligned with the interest of the public.

The following planner and/or their spouse/partner have reported no relevant financial relationship with a commercial interest:
Jacqueline Chu, MD
Virginia Triant, MD, MPH

The following planner and/or their spouse/partner have reported a relevant financial relationship with a commercial interest:
Rajesh T. Gandhi, MD
Grant Funding: Gilead, Merck, ViiV
Consultant: Theratechnologies; EMD Serono

The following speaker and/or their spouse/partner have reported a relevant financial relationship with a commercial interest:
Raymond Chung, MD
Grant Funding: AbbVie, Bristol-Myers Squibb, Gilead, Merck, Roche, Janssen

Hardware/Software Specifications: 

This internet-based CME activity is best experienced Microsoft Internet Explorer 9.0 or later, Mozilla Firefox 13 or later, Chrome 16 or later, Safari (version 5 or later)

This Web site requires that JavaScript and session cookies be enabled. Certain activities may require additional software to view multimedia, presentation, or printable versions of the content. These activities will be marked as such and will provide links to the required software. That software may be: Adobe Flash, Adobe Acrobat, and Microsoft PowerPoint.

Optimal System Configuration: 
Flash Player: Adobe Flash Player 10.1+
Browser: Firefox 13+, Internet Explorer 9.0+, Safari 13+, or Google Chrome 16+
Operating System: Windows Vista,7,8 or Mac OS X 10.4+
Internet Connection: 1 Mbps or higher

Minimum Requirements: 
Windows PC: 
Intel Pentium 4 or equivalent with 2.33 GHz processor; Windows XP; 512 MB RAM; Video Card at least 64MB of video memory; Sound Card at least 16-bit; Macromedia Flash Player 10 or higher, audio playback with speakers for programs with video content; Firefox 3+, Internet Explorer 7.0+, Safari 4+, Google Chrome, or Opera
Macintosh: 
Mac OS X 10.3 or higher with latest updates installed; 1.83MHz Intel Core Duo or faster; RAM: 128MB or more; Video Card: at least 128MB of video memory; Sound Card: at least 16-bit